Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA. Department of Epidemiology & Biostatistics, University of California San Francisco, 1450 3rd Street, San Francisco, CA 94158, USA. Department of Biostatistics, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA. Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA. Pathology Unit, Addarii Institute, S. Orsola-Malpighi Hospital, Via Pietro Albertoni, 15, 40138 Bologna, Italy. Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. Department of Nutrition, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA. Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, SE-171 77 Stockholm, Sweden.